|Contributions||Titov, IUriǐ Andreevich,|
|LC Classifications||QD426 A3913|
|The Physical Object|
|Number of Pages||362|
A. A. Akhrem Yu. A. Titov Moscow, July v Preface to the Russian Edition Steroids are one of the most interesting and most widely distributed and, at the same time, one of the most structurally complex groups of natural compounds. Book: All Authors / Contributors: A A Akhrem; I︠U︡ A Titov. Classes of steroid compounds.- History of total steroid synthesis.- Prospects for total synthesis.- 2. Building up of the steroid skeleton.- Methods of introducing side chains.- Methods of forming and transforming the rings.- Afanasii A. Akhrem and Yurii A. Titov. The book discusses the process of designing total syntheses; the biogenetic-like steroid synthesis, including cyclization of terminal epoxides as well as the total synthesis from nonepoxide precursors; and the synthesis of equilenin, estrone, bisdehydrodoisynolic acid, 18,bisnorprogesterone, norpregnanes, and heterocyclic Edition: 1. Abstract. This chapter includes both the earliest and the most recent methods for the total synthesis of steroids, In accordance with the methods of building up the steroid skeleton considered in it, the presentation of the material is divided into five : Afanasii A. Akhrem, Yurii A. Titov.
Though many aza steroids have been reported, curiously and much to our surprise, 3-aza-1,3,5(10)-trieno steroids have been reported only once and it was not a total synthesis. Nevertheless, a steroidal pyridine- N -oxide proved to be a potent inhibitor of the enzyme 5α-reductase (5AR) which catalyzes the conversion of testosterone to the more Cited by: 4. Cite this chapter as: Akhrem A.A., Titov Y.A. () General Questions of Total Synthesis. In: Total Steroid Synthesis. Springer, Boston, MAAuthor: Afanasii A. Akhrem, Yurii A. Titov. Jiwni of Stt'roid Bioffivim^tr Vol. i pp. 55 lo 60 Pergamon Press Ltd Prinled in Great Britain 1. Advances in Steroid Chemistry TOTAL SYNTHESIS OF NATURAL AND NON-NATURAL STEROID HORMONES ULRICH EDER Schering AG Research Laboratories, Berlin/Bergkamen, Federal Republic of Germany SUMMARY A number of steroid total syntheses, such as the synthesis of oestradiol, a Cited by: Akhrem Yu. A. Titov Moscow, July v Preface to the Russian Edition Steroids are one of the most interesting and most widely distributed and, at the same time, one of the most structurally.
Total Synthesis of Steroids: Organic Chemistry: A Series of Monographs, Vol. 30 Paperback – Octo by Robert T. Blickenstaff (Author) › Visit Amazon's Robert T. Blickenstaff Page. Find all the books, read about the author, and more. See search results for this author. Are you an author? Author: Robert T. Blickenstaff. Cite this chapter as: Akhrem A.A., Titov Y.A. () Total Syntheses from BC and BD Fragments. In: Total Steroid Synthesis. Springer, Boston, MAAuthor: Afanasii A. Akhrem, Yurii A. Titov. The synthetic building up of steroid compounds from bicyclic intermediate with potential C and D rings has been used for the synthesis of both aromatic and nonaromatic steroids. This approach is apparently the most laborious method and that with the largest number of stages for the synthesis of the various classes of steroid : Afanasii A. Akhrem, Yurii A. Titov. After papers on total steroid synthesis and related topics published by Igor Torgov and co-workers, it became possible to synthesize steroid hormones possessing a wide spectrum of biological activity, in particular d-estradiol, nortestosterone, hydroxysteroids, and even substituted scientists and technologists have also modified the Torgov reaction sequence to produce Cited by: 2.